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Literature summary extracted from

  • Fernandez, I.S.; Staendker, L.; Forssmann, W.G.; Gimenez-Gallego, G.; Romero, A.
    Crystallization and preliminary crystallographic studies of human kallikrein 7, a serine protease of the multigene kallikrein family (2007), Acta Crystallogr. Sect. F, F63, 669-672.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.4.21.117 gene KLK7, encoded on chromosome 19, expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)SS with secretion to the the bacterial periplasm Homo sapiens

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.21.117 purified recombinant His-tagged enzyme, sitting-drop vapour-diffusion method, 22°C, 0.0001 ml of 8 mg/ml protein in 50 mM sodium phosphate buffer, pH 7.5, mixed with 0.0001 ml of reservoir solution, X-ray diffraction structure determination and anaylsis at 2.8 A resolution Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.117 additional information Homo sapiens kallikrein 7 is involved in pathological keratinization, psoriasis and ovarian cancer ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.117 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.117 recombinant His-tagged enzyme from Escherichia coli strain BL21(DE3)SS periplasm by nickel affinity chromatography Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.117 ovary
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.117 additional information kallikrein 7 is involved in pathological keratinization, psoriasis and ovarian cancer Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.117 More molecular structure of kallikrein 7 Homo sapiens

Synonyms

EC Number Synonyms Comment Organism
3.4.21.117 kallikrein 7
-
 Homo sapiens
3.4.21.117 More the enzyme belongs to the multigene kallikrein serine protease family Homo sapiens